Accreditation

Please click here to upload full disclosure information for all presenters (pdf)

This activity has been approved for AMA PRA Category 1 Credit(s)TM.

Post Graduate Weekend (PGW): maximum of 12.75 hours

TTS 2010 Congress: maximum of 32.5 hours

TTS 2010 Congress and PGW: maximum of 45.25 hours

 

How to get your CME Certificate

CME Certificates will only be available online. To get your certificate, just go to http://www.gotomylist.com/evaluator/evaluation_start.cfm?pk_event=733

Password: TTS2010Congress

CME Screenshot

IMPORTANT!

The online certificate site will only be available through September 17, 2010.  After that date, the site will be removed and certificates will no longer be available.  If you need a CE certificate, you must complete the evaluation and certificate process prior to that date, otherwise you will forfeit your credit for the course.

On the site, you will be asked to enter a password (TTS2010Congress), and evaluate various aspects of the program.  You may then print your certificate immediately (encouraged), anywhere you have internet access.  A copy of the certificate will also be emailed to you in case you need to print additional copies (check your spam filter and junk email folder if you do not see it come through).  The email copy is simply a backup in case you didn’t print it right away.

Please address any questions about the CE process to:  Jay Parker, Phone +1 651-789-3716, Fax +1 651-489-3387

Congress Learning Objectives

After attending the XXIII Congress and Post Graduate Weekend, attendees will be able to:

  • Discuss genetics and molecular sciences relating to transplantation biology and human immunology;
  • Review therapeutic immunosuppression and manipulation of the immune response to minimize graft rejection;
  • Explore the prediction, prevention and treatment of adverse events and complications of transplantation;
  • Integrate information on long-term clinical outcomes after transplantation;
  • Discuss societal, legal and ethical issues of organ retrieval and replacement.

Topical Learning Points

Organ donation

  • Explain organ donation from deceased donors.
  • Name different international strategies to improve organ donation from deceased donors.
  • Describe principles of organ allocation.
  • Discuss about pros and cons of living donation.
  • Explain different points of view related to living donation.
  • Discuss about different donor exchange programs.
  • Enumerate strategies to optimize management of organ donors.
  • Debate about organ trafficking and commercialism.
  • Discuss about different topics related to organ donation and allocation to reduce the number of patients on the waiting list.
  • Describe international strategies in organ donation.

Immunosuppression

  • Explain ways to design and interpret clinical studies.
  • Name and explain different induction strategies.       
  • Describe risks and benefits of maintenance immunosuppressive protocols.
  • Name therapeutic strategies used in recipients of solid organ transplants with chronic kidney disease.    
  • Name factors associated with the development of malignancies.    
  • Describe new and current immunosuppressive strategies in patients with post-transplant malignancies.
  • Describe factors influencing antibody mediated rejection.    
  • Differentiate acute and chronic antibody mediated rejection.           
  • Discuss prevention and treatment of antibody mediated rejection in heart and renal transplantation.
  • Describe the use of biomarkers.
  • Explain the clinical value of therapeutic drug monitoring.
  • Evaluate the ethical responsibilities of clinical investigators.
  • Design and interpret different types of clinical studies, including RCT.
  • List and describe new immunosuppressive agents. 
  • List and describe immunosuppressive agents under development.
  • Describe and assess clinical trials of immunosuppression.
  • Describe the risks and benefits of m-TOR inhibitors and mycophenolic acid (MPA).
  • Discuss about the risks and benefits of CNI minimization strategies.
  • Discuss about pharmacokinetics, pharmacodynamics and pharmacogenomics of different immunosuppressive agents.
  • Describe new strategies in immunosuppression.
  • Discuss about complications related to immunosuppressive agents.

The role of the immune system in transplantation

  • Discuss about immune mechanisms in transplantation and autoimmunity.
  • Discuss about molecular and cellular mechanisms involved in tolerance.
  • Describe the role of T regs and B regs cells in transplantation.
  • Summarize the role of B cells in rejection and tolerance.
  • Compare the role of innate to adaptive immunity.
  • Describe the role of NK cells in graft injury and acceptance.
  • List different types of T cells and discuss about their role in transplantation.
  • Discuss about inducing transplantation tolerance.

New techniques: xenotransplantation, stem cells, mixed tissue transplantation

  • Describe the benefits and challenges of the use of stem cells in transplantation.
  • Summarize new advances in regenerative medicine developed for clinical use.
  • Discuss about benefits and challenges of mixed tissue transplantation.
  • Define tissue engineering and discuss about its application in transplantation.
  • Name and describe new developments in xenotransplantation.
  • Discuss about the benefits and challenges of the use of mesenchymal stem cells and cellular transplantation.

Kidney transplantation

  • Describe strategies to optimize immediate graft function in kidney transplantation.
  • Discuss options and outcomes in sensitized kidney transplant recipients.
  • Discuss about clinical strategies and outcomes in kidney transplantation.
  • Describe diagnostics techniques in kidney transplantation.
  • Discuss molecular mechanisms of delayed graft function.
  • Describe molecular mechanisms of chronic kidney graft injury.
  • Explain biomarkers in kidney transplantation.

Islets cells and pancreas transplantation

  • Describe the role of auto and alloimmnunity in clinical islet transplantation.
  • Discuss about clinical results of islet auto transplantation.
  • Summarize the impact of islet transplantation on metabolic issues.
  • Explain the impact of islet and pancreas transplantation on secondary complications.
  • Discuss about islet and pancreas allocation.
  • Describe outcomes in islet and pancreas transplantation.
  • Discuss about new information on experimental islet transplantation.

Antibodies against HLA and non-HLA antigens

  • Explain the importance and evolution of tissue typing.
  • Discuss about the clinical applications of testing for HLA antibodies.
  • Discuss about the clinical implications of antibodies to transplantation antigens.
  • Describe different methods to test for antibodies to transplantation antigens.
  • Discuss immunosuppression in highly sensitized patients.
  • Describe diagnosis and treatment of acute and chronic AMR

Liver transplantation

  • Discuss living donor issues in liver transplantation.
  • Describe selection criteria for patients with Hepatocellular carcinoma(HCC).
  • Discuss about pre-transplant treatment of patients with HCC.
  • Name risk factors for Hepatitis C (HCV) recurrence.
  • Describe treatments for HCV recipients and for HCV recurrence.
  • Discuss about pharmacological and non-pharmacological strategies to prevent graft injury.
  • Describe new immunosuppressive strategies in liver transplantation.
  • Discuss clinical outcomes in liver transplantation.
  • Describe results in living donor liver transplantation.
  • Discuss treatment strategies in liver transplant recipients with viral hepatitis.
  • Discuss about tolerance in liver transplantation.

Lung transplantation

  • Name recipient and donor characteristics associated with primary graft dysfunction
  • Discuss about causes related to chronic lung allograft dysfunction
  • Describe the impact of donor specific antibodies in post lung transplant
  • Discuss about experimental and clinical issues in lung transplantation.

Biological and technical issues in organ harvest and preservation

  • Discuss about organ preservation.
  • Describe the relationship between the biology of brain death and organ damage.
  • Indicate the role of the immune system (innate and adaptive) in ischemia-reperfusion injury.
  • List different strategies used for cytoprotection in ischemic organ injury.
  • Summarize available organ preservation solutions.
  • Discuss about experimental ischemia and reperfusion injury topics.

Heart transplantation

  • Discuss the  management of organ donors and post-operative strategies.
  • Explain the mechanisms of ischemia reperfusion injury.
  • Describe the peri-operative managementof the heart transplant recipient.
  • Describe new biologic and therapeutic advances in heart transplantation.
  • Discuss about cardiac evaluation.

Intestine transplantation

  • Describe different intestine rehabilitation options.
  • Discuss about basic science concepts of intestinal transplantation.
  • Discuss about clinical outcomes for intestinal transplantation.
  • Describe new advances in intestinal and multivisceral transplantation.

Genomics and Proteomics

  • Summarize the role of genomics and proteomics in transplantation.
  • Discuss about the use of microarrays.
  • Discuss about pharmacogenomics in transplantation.
  • Report new advances in “Transplantomics”.
  • Discuss about integrative genomics in organ transplantation.
  • Name genetic and molecular mechanisms implicated in chronic allograft injury, tissue injury and remodeling.
  • Discuss about tissue inflammation and repair.
  • Describe the use of biomarkers of injury and response in transplanted patients.
Diagnostics
  • Discuss about new concepts described in the last Banff classification.
  • Apply the new Banff classification to the interpretation of renal transplant biopsies.
  • Describe key histological characteristics of acute rejection and AMR.
  • Explain the use of microarrays in the diagnosis of acute cellular and antibody-AMR
  • Discuss biomarkers and immunosuppression.
  • Discuss about molecular and cellular pathology of the kidney allograft
Advancing your career while improving science: Writing grants, publishing papers, interpreting randomized controlled trials and giving high impact presentations
  • Indicate the ethical responsibilities of the investigators.
  • Explain how to design a study.
  • Interpret RCT.
  • Describe ways of writing grant applications.
  • Analyze, choose and apply different techniques to write scientific manuscripts.
  • Apply different techniques to give high impact presentations.

Pediatric transplantation

  • Discuss immunosuppression in pediatric transplantation.
  • Describe outcomes in pediatric transplantation.

Infections

  • Discuss donor related infections.
  • Explain strategies to prevent and treat H1N1 infection.
  • Describe diagnosis and treatment of BK infection.
  • Discuss current management of patients with HIV, HBV, HCV.
  • Explain new treatment strategies for CMV.
  • Discuss non-viral infections in transplant recipients.

Nursing

  • Discuss about issues related to interprofessional practice.
  • Describe risk taking behavior in transplant recipients.
  • Explain current trends in the area of transplanting foreign nationals

 

Please continue to visit the website for the most up to date information and
Join the Mailing List to receive important announcements regarding the Congress.